Icodextrin with nitroprusside increases ultrafiltration and peritoneal transport during long CAPD dwells

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Superiority of icodextrin compared with 4.25% dextrose for peritoneal ultrafiltration.

Several clinical observations suggest the superiority of icodextrin compared with 4.25% dextrose in optimizing peritoneal ultrafiltration (UF), but no rigorous controlled evaluation has hitherto been performed. For comparing icodextrin and 4.25% dextrose during the long dwell of automated peritoneal dialysis, a multicenter, randomized, double-blind trial was conducted in 92 patients (control, 4...

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Hypertonic glucose-based peritoneal dialysate is associated with higher blood pressure and adverse haemodynamics as compared with icodextrin.

BACKGROUND Little is known about the haemodynamic effects of continuous ambulatory peritoneal dialysis (CAPD) despite its widespread use in the management of end-stage renal failure. We undertook a study to delineate the haemodynamic effects of CAPD using glucose-containing fluids (1.36 and 3.86% glucose) and icodextrin. METHODS Eight CAPD patients were recruited for a prospective crossover s...

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Comparison of volume overload with cycler-assisted versus continuous ambulatory peritoneal dialysis.

BACKGROUND AND OBJECTIVES Cycler-assisted peritoneal dialysis (CCPD) has been associated with decreased sodium removal compared with continuous ambulatory peritoneal dialysis (CAPD) as a result of peritoneal sodium sieving during the short dwells that are associated with CCPD. This may have adverse consequences for management of extracellular fluid volume (ECFV). This study compared ECFV in pat...

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Sodium removal in peritoneal dialysis: the role of icodextrin and peritoneal dialysis modalities.

One of the main goals of dialysis is the control of extracellular volume, because inadequate sodium and fluid removal result in fluid overload and increased mortality. In the present study, we evaluated the roles of continuous ambulatory peritoneal dialysis (CAPD), continuous cycling peritoneal dialysis (CCPD), and the use of icodextrin on sodium removal in 29 patients (n = 18 on CAPD, n = 11 o...

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Randomized controlled trial of icodextrin versus glucose containing peritoneal dialysis fluid.

BACKGROUND AND OBJECTIVES While peritoneal dialysis with icodextrin is commonly used in patients with poor peritoneal membrane characteristics, the data on the usefulness of this solution in patients with lower transport characteristics are limited. The study was designed to compare icodextrin to glucose in Chinese prevalent peritoneal dialysis patients of different peritoneal transport charact...

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ژورنال

عنوان ژورنال: Kidney International

سال: 1998

ISSN: 0085-2538

DOI: 10.1111/j.1523-1755.1998.00821.x